Every Contribution Matters

Research is vital in increasing our understanding of HD, improving the quality of life for those impacted by HD, and also providing hope for viable treatments and a cure.

Research continues to progress through the collaboration between you-our community, our invaluable HD researchers and your association. When you participate in research, your contribution not only helps in the study you are involved in, but is often a starting point for new or further research.

Huntington’s Victoria proudly partners with the Huntington’s Research Group of Victoria (HRGV) who are extremely active in HD research. You can view some of the local research below, and find out how you can become involved.

Local Research

Improving the Usefulness of a Driving App in Huntington’s Disease

Address: Room 408, Level 4, 18 Innovation Walk, Clayton, VIC 3800

We want to investigate a new app which we hope will assist both patients and health professionals to better understand how someone’s driving is going. On-road driving assessments can be quite expensive, and so we are hoping to improve a specially designed iPad app that could save people from going for an expensive driving assessment before they need to.


What causes Huntington’s disease and what role do genes and environment play?

NHMRC Principal Research Fellow and Laboratory Head, Florey Institute of Neuroscience and Mental Health

Over the past two decades, our research team has played a key role in understanding how the ‘genetic stutter’ causing Huntington’s disease (HD) leads to a cascade of pathological processes, at the levels of molecules, cells, brain circuits, behaviour, cognition and mood. HD is one of a growing number of human diseases known to be caused by such ‘genetic stutters’, which are called tandem repeat disorders (reviewed by Hannan, 2018, Nature Rev. Genet.)


Can Non-Invasive Brain Stimulation be used to treat apathy in Huntington’s Disease?

Epworth Centre for Innovation in Mental Health (ECIMH), Epworth Clinic, 888 Toorak Road, Camberwell VIC 3124

There are currently no effective treatments for apathy (loss of motivation) caused by HD. I am conducting this study to find out whether transcranial alternating current stimulation (tACS), a gentle non-invasive brain stimulation technique, can alter brain activity in a way that may be used to increase motivation in people with Huntington’s disease (HD).

See more research

International Research

Wave Life Sciences clinical trials


Wave Life Sciences PRECISION- HD1 and PRECISION-HD2 Clinical trials   Wave Life Sciences are conducting two Phase 1b/2a clinical trials called PRECISION-HD1 and PRECISION-HD2. These trials aim to specifically target and reduce the amount of mutant huntingtin protein produced, whilst leaving the healthy huntingtin protein untouched. The treatments will be administered into the fluid in the […]